Hance is an English and French surname. Notable people with the surname include:

Benjamin Hance (born 2000), Australian Paralympic swimmer Blake Hance (born 1996), American football player Guy Hance (1933–2008), Belgian politician Henry Fletcher Hance (1827–1886), British diplomat and botanist whose standard author abbreviation is Hance Kent Hance (born 1942), American academic administrator Rei Hance (born 1974 as Heather Donahue), American actress and writer William Henry Hance (1951–1994), American soldier and serial killer