This is a list of psychedelic drugs, also known as serotonergic psychedelics or classical hallucinogens. These drugs act specifically as serotonin 5-HT2A receptor agonists. They belong to three major structural families, including the tryptamines, phenethylamines, and lysergamides, although exceptions exist.
No ring substitutions
N-(2-Cyanoethyl)tryptamine (CE-T) Deudimethyltryptamine (DMT-d10; HLP004; CYB004) Diallyltryptamine (DALT) Dibutyltryptamine (DBT) Diethyltryptamine (DET; T-9) Diisopropyltryptamine (DiPT) Dimethyltryptamine (DMT) Dimethyltryptamine-d4 (DMT-d4; D4DMT) Dipropyltryptamine (DPT) Ethylisopropyltryptamine (EiPT) Ethylpropyltryptamine (EPT) Isopropylallyltryptamine (iPALT; ALiPT) Methylallyltryptamine (MALT) Methylcyclopropyltryptamine (McPT) Methylethyltryptamine (MET) Methylisopropyltryptamine (MiPT) Methylpropyltryptamine (MPT) N-Methyltryptamine (NMT) N-Phosphonooxymethyl-DMT (N-POM-DMT) Propylallyltryptamine (PALT) Propylisopropyltryptamine (PiPT) SPL028 (D2-DMT) Tryptamine (T)
4-Hydroxytryptamines
1-Methylpsilocin (CMY, CMY-16) 4-HO-DALT (daltocin) 4-HO-DBT 4-HO-DET (ethocin; CZ-74) 4-HO-DiPT (iprocin) 4-HO-DPT (deprocin) 4-HO-EPT (eprocin) 4-HO-MALT (maltocin) 4-HO-McPT 4-HO-MET (metocin) 4-HO-MiPT (miprocin) 4-HO-MPT (meprocin) 4-HO-NALT 4-HO-NBnT 4-HO-NET 4-HO-NiPT 4-HO-NPT 4-HO-TMT 4-HO-5-MeO-DMT 4-Hydroxytryptamine (4-HO-T; 4-HT) Deupsilocin (HLP003; CYB003) Psilocin (4-HO-DMT; CX-59) Psilomethoxin (5-MeO-4-HO-DMT)
4-Phosphoryloxytryptamines
5-Methoxypsilocybin (5-MeO-4-PO-DMT) 5-Methylpsilocybin (5-Me-4-PO-DMT) Aeruginascin (4-PO-TMT) Baeocystin (4-PO-NMT) Ethocybin (4-PO-DET; CEY-19) Norbaeocystin (4-PO-T) Psilocybin (4-PO-DMT; CY-39)
4-Acyloxytryptamines
4-AcO-DALT (daltacetin) 4-AcO-DET (ethacetin) 4-AcO-DiPT (ipracetin) 4-AcO-DMT (psilacetin) 4-AcO-DPT (depracetin) 4-AcO-EiPT (ethipracetin) 4-AcO-EPT 4-AcO-MALT 4-AcO-McPT 4-AcO-MET (metacetin) 4-AcO-MiPT (mipracetin) 4-AcO-MPT 4-GO-DMT (RE-109) 4-PrO-DiPT 4-PrO-DMT 4-PrO-MET Luvesilocin (4-GO-DiPT; RE-104, FT-104)
5-Hydroxytryptamines
5-HO-MET Bufotenin (5-HO-DMT) Serotonin (5-HT; 5-HO-T)
5-Acyloxytryptamines
O-Acetylbufotenine (5-AcO-DMT) O-Pivalylbufotenine (5-t-BuCO-DMT)
5-Methoxytryptamines
4-HO-5-MeO-DMT 5-MeO-2,N,N-TMT 5-MeO-DALT 5-MeO-DBT 5-MeO-DET 5-MeO-DiPT 5-MeO-DMT (mebufotenin) 5-MeO-DMT-d4 5-MeO-DPT 5-MeO-EiPT 5-MeO-MALT 5-MeO-MET 5-MeO-MiPT 5-MeO-MsBT 5-MeO-NiPT 5-MeO-NMT 5-MeO-T-NBOMe 5-MeO-T-NB3OMe 5-Methoxytryptamine (5-MeO-T; 5-MT) ASR-3001 (5-MeO-iPALT) NB-5-MeO-DALT NB-5-MeO-MiPT
Other ring substitutions
1-Acetyl-5-MeO-DMT 1-Benzoyl-DMT 2-Methyltryptamine 2,N,N-TMT (2-methyl-DMT) 4,N,N-TMT (4-methyl-DMT) 4-MeS-DMT 5-Bromo-DMT 5-Chloro-DMT 5-Fluoro-DMT 5-MeS-DMT 5-Nitro-T (Nitro-I) 5-PhO-T (OVT2) 5-N,N-TMT (5-methyl-DMT) 7,N,N-TMT (6-methyl-DMT) 5-MeO-2,N,N-TMT 6-Fluoro-DMT 6-Hydroxy-DET (6-HO-DET) 6-TFMO-DMT Bretisilocin (GM-2505; 5-fluoro-MET) HBL20016 (5-MeS-6-F-DMT) NBoc-DMT (NB-DMT)
α-Alkyltryptamines
4-HO-AMT 4-Methyl-AMT 5-Fluoro-AMT 6-Fluoro-AMT AMT (Indopan) α-Methylserotonin (5-HO-αMT) α,N,N-TMT (α-Me-DMT; Alpha-N) N-Hydroxy-AMT
5-Methoxy-α-alkyltryptamines
5-MeO-AET 5-MeO-AMT (α,O-DMS; Alpha-O) α,N,O-TMS (5-MeO-α,N-DMT) α,N,N,O-TeMS (5-MeO-α,N,N-TMT)
Others
N-DEAOP-Ts (e.g., N-DEAOP-NET, N-DEAOP-NMT, 5-MeO-N-DEAOP-NMT, 5-MeO-N-DEAOP-NET)
Structure undisclosed
CT-4201 EB-002 (EB-373) MSP-1014 MYCO-004
Ergolines/lysergamides (e.g., LSD) Ibogalogs (e.g., ibogainalog, tabernanthalog, Pharm-136) O-Methylnordehydrobufotenine Partial ergolines (e.g., NDTDI, RU-28306, CT-5252) Piperidinylethylindoles (e.g., pip-T) Pyrrolidinylethylindoles (e.g., pyr-T, 5-MeO-pyr-T) Pyrrolidinylmethylindoles (e.g., MPMI, 4-HO-MPMI (lucigenol), 5-MeO-MPMI, MSP-2020) Tetrahydropyridinylindoles (e.g., RU-28253, NEtPhOH-THPI)
Unknown psychedelic activity β-Carbolines (e.g., pinoline, 1-ethyl-6-hydroxytryptoline, 1-(2,4,5-trimethoxyphenyl)-6-chlorotryptoline)
Benzofurans (e.g., 5-MeO-DiBF (1-oxa-5-MeO-DiPT), dimemebfe (5-MeO-BFE; 1-oxa-5-MeO-DMT), mebfap (5-MeO-3-APB; 1-oxa-5-MeO-AMT)) Benzothiophenes (e.g., 3-APBT (1-thia-AMT)) Indazolethylamines (e.g., AL-38022A, O-methyl-AL-34662) Indenylethylamines (e.g., C-DMT) Isotryptamines (e.g., 6-MeO-isoDMT, Ro60-0175) MYCO-005
Unknown psychedelic activity Quinolinylethylamines (e.g., mefloquine)
2-Bromomescaline 4-D (4-trideuteromescaline) Allylescaline (AL) Alpha-D (α-D; α,α-dideuteromescaline) Alpha,Beta-D (α,β-D; α,β-dideuteromescaline) Beta-D (β-D; β-dideuteromescaline) Cyclopropylmescaline (CPM) Difluoroescaline (DFE) Difluoromescaline (DFM) N,N-Diformylmescaline Escaline (E) Fluoroescaline (FE) Fluoroproscaline (FP) N-Formylmescaline Isobuscaline (IB) Isoproscaline (IP) Mescaline (M; 3,4,5-TMPEA) Metadifluoromescaline (MDFM) Metaescaline (ME) Methallylescaline (MAL) N-Methylmescaline (M-M) Proscaline (P) Trichocereine (N,N-dimethylmescaline; MM-M) Trifluoroescaline (TFE) Trifluoromescaline (TFM)
Thioscalines
3-Thioasymbescaline (3-TASB) 3-Thioescaline (3-TE) 3-Thiomescaline (3-TM) 3-Thiometaescaline (3-TME) 4-Thioasymbescaline (4-TASB) 4-Thioescaline (4-TE) 4-Thiomescaline (4-TM) 5-Thioasymbescaline (5-TASB) Thiobuscaline (TB; 4-TB) Thioproscaline (TP; 4-TP)
Desoxyscalines 4-Desoxymescaline (desoxy, desoxymescaline)
Others
Jimscaline Tomscaline
2C-B 2CB-2OCD3 2CB-5OCD3 2C-Bu 2C-C 2C-CN 2C-CP 2C-D 2C-E 2C-EF 2C-F 2C-H 2C-I 2C-iBu 2C-iP 2C-N 2C-P 2C-Se 2C-Se-TFM 2C-tBu 2C-TFE 2C-TFM 2C-YN 2C-V
2C-T-x
2C-T 2C-T-2 2C-T-3 (2C-T-20) 2C-T-4 2C-T-7 2C-T-8 2C-T-9 2C-T-13 2C-T-15 2C-T-16 2C-T-17 2C-T-19 2C-T-21 2C-T-21.5 2C-T-22 2C-T-25 2C-T-27 2C-T-28 2C-T-30 2C-T-36 (2C-T-TFM; CYB210010; CYB2108) CYB2108D (deuterated 2C-T-36)
2C-O-x
2C-O (2,4,5-TMPEA; TMPEA-2) 2C-O-4 2C-O-22
Others
2C-B-AN 2C-DB 2C-G-x (e.g., 2C-G-3, 2C-G-5) β-Keto-2C-B (βk-2C-B) β-Keto-2C-I (βk-2C-I) β-Methyl-2C-B (BMB) (e.g., BOB, BOD, BOHB) (e.g., HOT-2, HOT-7, HOT-17) N-Ethyl-2C-B (e.g., 2CB-2-EtO, 2CD-2-EtO, 2CD-5-EtO, 2CE-5-EtO, 2CE-5iPrO, 2CT-5-EtO, 2CT2-2-EtO, 2CT7-2-EtO, ASR-2001 (2CB-5-PrO))
3C-AL 3C-BZ 3C-DFE 3C-E 3C-FP 3C-MAL 3C-P TMA (3C-M)
DOAM DOB DOBU DOC DOEF DOET DOH (2,5-DMA) DOI DOIB DOIP DOM DON DOPR DOTFM DOYN
Aleph-x (DOT-x)
Aleph (DOT) Aleph-2 Aleph-4 Aleph-6 Aleph-7
TMA-2 and derivatives (Mxx)
MALM MEM MDFEM MFEM MIPM MMALM MPM MTFEM TMA-2
Others
DODB DODC DOM-NBOMe DOTMA Ganeshas (G-x) (e.g., Ganesha (G, G-0), G-3, G-5) MME (TMA2-5-EtO) N-Hydroxy-DOM
4C-B 4C-D (Ariadne) 4C-I 4C-P (4C-Pr) 4C-T-2 4C-TFM
2,4,6-TMPEA-NBOMe Ψ-2C-DFMO (ψ-2C-O-35) Ψ-2C-T-4 Ψ-DODFMO Ψ-DOM TMA-6 (Ψ-TMA-2)
5-Methyl-MDA 6-Methyl-MDA DMMDA DMMDA-2 EIDA EMDA-2 IDA Lophophine (MMDPEA) Lys-MDA MDA (tenamfetamine) MDHMA (FLEA; MDMOH) MDMA (midomafetamine; ecstasy) MDOH MMDA MMDA-2 MMDA-3a MMDA-3b MMDMA N-t-BOC-MDMA (R)-MDMA
2C-B-FLY 2C-B-DragonFLY 2C-E-FLY 2C-EF-FLY 2C-I-FLY 2CBFly-NBOMe Bromo-DragonFLY DOB-FLY DOH-FLY TFMFly
Hemi/semi-FLY drugs
DOH-5-hemiFLY (semi-fly; SF) DOB-5-hemiFLY (bromo-semi-fly; B-SF)
25x-NBOMe
25B-NBOMe 25C-NBOMe 25CN-NBOMe 25D-NBOMe 25E-NBOMe 25F-NBOMe 25G-NBOMe 25H-NBOMe 25I-NBOMe 25iP-NBOMe 25N-NBOMe 25O-NBOMe 25P-NBOMe 25T-NBOMe 25T2-NBOMe 25T4-NBOMe 25T7-NBOMe 25TFM-NBOMe
25x-NBOH
25B-NBOH 25C-NBOH 25CN-NBOH 25E-NBOH 25I-NBOH
25x-NBF
25B-NBF 25C-NBF 25I-NBF
Others
2,4,6-TMPEA-NBOMe 25B-NB (N-benzyl-2C-B) 2C-B-AN 2C2-NBOMe 2CBCB-NBOMe 2CBFly-NBOMe DOM-NBOMe NBOMe-escaline NBOMe-mescaline TGF-8027
Others
2-DM-DOM 25B-NAcPip 4-HA 5-DM-DOM Benzofurans (e.g., 5-APB, 5-APDB, 6-APB, 6-APDB, F, F-2, F-22) Benzothiophenes (e.g., 5-APBT, 6-APBT) BMB-202 CT-5172 DMAs (e.g., 2,4-DMA, 3,4-DMA) Fenfluramine MMA (3-MeO-4-MA) Norfenfluramine (e.g., 25D-NM-NDEAOP, DOB-NDEPA, DOI-NDEPA, DOM-NDEPA, DOTFM-NDEPA, M-NDEPA, TMA-2-NDEPA) PMA (4-MA) Thio-2Cs (e.g., 2C-5-TOET) Thio-DOx (e.g., 2-TOM, 5-TOET, 5-TOM, TOMSO) (e.g., TMA-3, TMA-4, TMA-5) ZDCM-04 (DOC-fenethylline)
Structure undisclosed
HLP005 (CYB005)
1-Aminomethylindanes (e.g., 2CB-Ind, jimscaline) 2-Aminoindanes (e.g., DOM-AI) 2-Aminotetralins (e.g., UH-232) 3-Benzazepines (e.g., lorcaserin) 3-Phenylpiperidines (e.g., LPH-5, LPH-48) Benzocyclobutenes (e.g., 2CBCB-NBOMe, TCB-2, tomscaline) Benzoxepins (e.g., BBOX, IBOX, TFMBOX) DMBMPP (juncosamine) Ergolines/lysergamides (e.g., LSD) Partial ergolines (e.g., NDTDI, UCD0179, UCD0120, UCD0120-M, UCD0120-NAP) Phenylcyclopropylamines (e.g., DMCPA, TMT) Phenyloxazolamines (aminorexes) (e.g., 2C-B-aminorex) Pyridopyrroloquinoxalines (e.g., IHCH-7113) Z3517967757 ZC-B
Unknown psychedelic activity Aporphines and noraporphines (e.g., glaucine, 11-methoxyasimilobine, 2-hydroxy-11-(2-methylallyl)oxynoraporphine)
No substitutions
Ergine (LSA, LA-111) Isoergine (iso-LSA, iso-LA)
Amide-substituted lysergamides
DAL DAM (DAM-57) DiPLA DPL EcPLA EiPLA EPLA (LEP; LEP-57) Ergometrine (ergonovine, ergobasine) ETFELA iPLA LA-3Cl-SB (Cl-LSB) LAE (LAE-32) LAM LAMPA LAP LME (LME-54) LMP (LMP-55) LPD (LPD-824) LSB LSD (LSD-25, METH-LAD; lysergide) LSD-Pip LSDP (DPL) LSH (LAH) LSM (LSM-775) 2-LSP LSP (3-LSP) LSZ (LA-SS-Az) Lysergic acid pyrrolinide (LPN) Methylergometrine (methylergonovine, methylergobasine) MiPLA
6-Alkyllysergamides
BU-LAD CE-LAD (CHLORETH-LAD) CPM-LAD CYP-LAD (TRALA-22) ETH-LAD FLUORETH-LAD (FE-LAD) FP-LAD IP-LAD NBOMe-LAD PARGY-LAD PRO-LAD
1-Alkyllysergamides (prodrugs)
Methysergide (1-methylmethylergonovine; UML-491) MLA-74 (1-methyl-LAE) MLD-41 (1-methyl-LSD) MPD-75 (1-methyl-LPD) OML-632 (1-hydroxymethyl-LSD)
1-Acyllysergamides (prodrugs)
1-Formyl-LSD 1B-LSD 1BP-LSD 1Bz-LSD 1cP-AL-LAD 1cP-LSD 1cP-MiPLA 1D-AL-LAD 1D-LSD 1DD-LSD 1F-LSD 1Fe-LSD 1H-LSD 1P-AL-LAD 1P-ETH-LAD 1P-LSD 1P-MiPLA 1S-LSD 1SB-LSD (1BS-LSD; 1-TMSBz-LSD) 1T-AL-LAD 1T-LSD 1V-LSD ALA-10 (1-acetyl-LAE; 1A-LAE) ALD-52 (1-acetyl-LSD; 1A-LSD)
Others
2,3-Dihydro-LSD 12-Hydroxy-LSD 12-Methoxy-LSD 14-Methyl-LSD
Lysergamide bioisosteres
JRT (isotryptamine-LSD)
Others
9-Oxaergolines (e.g., RU-29717) γ-Carbolines (e.g., tiflucarbine) Arylpiperazines (e.g., 2C-B-PP, 2-NP, mCPP, MK-212, ORG-12962, pCPP, pFPP, quipazine, TFMPP, VCU-1012) Dihydrobenzoxazines (e.g., efavirenz) Phenoxyethylamines (e.g., CT-4719, ORG-37684) Pyridopyrroloquinoxalines (e.g., IHCH-7113) Quinazolinylethylamines (e.g., RH-34)
Structure undisclosed
EGX-A EGX-B Lucid-PSYCH (Lucid-201) MSP-4018 MSP-4019 MSP-4020
Natural sources
Tryptamines
Acacia spp. (e.g., Acacia acuminata, Acacia confusa) Ayahuasca and vinho de Jurema (e.g., Psychotria viridis (chacruna), Dipolopterys cabrerana (chaliponga, chacruna), Mimosa tenuiflora (Mimosa hostilis; jurema)) Brosimum (e.g., Brosimum acutifolium (takini)) Hallucinogenic snuffs (e.g., Anadenanthera peregrina (yopo, jopo, cohoba, parica, ebene), Anadenanthera colubrina (vilca, cebil)) Incilius alvarius (Bufo alvarius; Colorado River toad, Sonoran Desert toad; bufo) Psilocybin-containing mushrooms (magic mushrooms, shrooms) (e.g., Psilocybe cubensis, Psilocybe mexicana (teonanacatl))
Phenethylamines
Pachycereus pringlei (saguesa, elephant cactus, cardon) Peyote (Lophophora williamsii; peyotl) Echinopsis cacti (e.g., San Pedro, Peruvian torch)
Lysergamides
Achnatherum robustum (sleepy grass) Epichloë spp. Ergot (Claviceps) (e.g., Claviceps purpurea, Claviceps paspali) Morning glory (Convolvulaceae) seeds (e.g., Ipomoea tricolor (tlitliltzin, badoh negro; Ipomoea violacea), Ipomoea corymbosa (coaxihuitl, ololiúqui; Rivea Corymbosa, Turbina Corymbosa), Argyreia nervosa (Hawaiian baby woodrose; HBWR))