CRF or crf may refer to:
Science and technology Corticotropin-releasing factor family, a family of related neuropeptides in vertebrates Corticotropin-releasing hormone, or corticotropin-releasing factor, a polypeptide hormone Chromatographic response function, a coefficient which characterizes the quality of the separation in the result of a chromatography Coefficient of rolling friction, a coefficient that measures the rolling resistance Cloud radiative forcing, the difference between the radiation budget components for average cloud conditions and cloud-free conditions Chemotactic range fitting, a phenomenon in which organisms direct their movements according to certain chemicals Controlled-release fertiliser, a solid form fertilizer Coupled rangefinder camera, a camera fitted with a rangefinder Case report form, a document in clinical trial research
Computing Conditional random field, in machine learning, a type of graphical model Constant Rate Factor, in video encoders (x265, and VP9, and AV1), a bitrate control method
Medicine Cardiorespiratory fitness, a medical term Case report form, in a clinical trial, the document showing all the evaluated patient data Cancer-related fatigue, fatigue experienced with cancer patients Chronic renal failure, also known as chronic kidney disease (CKD)
Economics and finance Capital recovery factor, a financial concept Consolidated Revenue Fund, the main government bank account in many Commonwealth Nations
Organisations Coalition for Religious Freedom, a group affiliated with the Unification Church also aka International Coalition for Religious Freedom Catholic Reaction Force, a name used by paramilitaries to issue death threats against Protestants in Northern Ireland during "The Troubles" Cave Research Foundation, an American private, non-profit group dedicated to the exploration, research, and conservation of caves Central Readiness Force, a military defense unit in Japan Centro Ricerche Fiat, the central research organization for Fiat; see Blue&Me Air Central (Japan), a defunct regional airline of Japan (1988–2010)
Sports Circle rules football, a variation on football with only one goal Cyprus Rugby Federation, the governing body for rugby union in Cyprus Clube de Regatas do Flamengo, a Brazilian football club based in Rio de Janeiro
Other uses Honda CRF series, a series of motorcycles Carolina Renaissance Festival, a festival held annually in North Carolina, United States Charter of Rights and Freedoms, a bill of rights entrenched in the Constitution of Canada Caramanta language, an ISO 639-3 code