Chambliss is a surname. Notable people with the surname include:
Chaz Chambliss (born 2002), American football player Chris Chambliss (born 1948), American baseball player Clyde Chambliss (born 1969), American politician John R. Chambliss (1833–1864), American soldier John R. Chambliss Sr. (1809–1875), American politician Kirby Chambliss (born 1959), American flier Robert Edward Chambliss (1904–1985), American domestic terrorist Saxby Chambliss (born 1948), American politician, Senior Senator from Georgia Trinidad Chambliss (born 2002), American football player William Chambliss (1933–2014), American criminologist, sociologist, and teacher William V. Chambliss (1866–1928), American businessperson, planter, and teacher
Other uses
Chambliss, Texas, an unincorporated community