Mohammad Yusef Khan, and other spellings, may refer to:
Muhammad Yousuf Khan or Dilip Kumar (1922–2021), Indian film actor Mohammad Yusuf Khan, father of Mohammad Nadir Shah, king of Afghanistan, 1929–1933 Mohammad Yusuf (politician) (aka, Mohammad Yusuf Khan, 1917–98), prime minister and foreign minister of Afghanistan Muhammed Yusuf Khan or Maruthanayagam Pillai (1725–1764), Indian soldier and later commandant of British East India Company troops
See also Yusuf Khan (disambiguation) Muhammad Khan (disambiguation) Mohammad Yousuf (disambiguation)