PUF is short for Presses Universitaires de France, a French publishing house.
It may also refer to:
Physical unclonable function, in computer security, a physically implemented secure identifier Permanent University Fund, for Texas public universities Pau Pyrénées Airport in France (IATA code: PUF) Por Um Fio, a Brazilian reality television show Poughkeepsie Underwear Factory, a historic building in New York Public Universal Friend (1752–1819), American preacher