CLIC or Clic can refer to:
Science and Technology Chloride intracellular channel (a type of chloride channel, consists of six conserved proteins in humans (CLIC1, CLIC2, CLIC3, CLIC4, CLIC5, CLIC6) Clathrin-independent carrier (a subtype of endocytic membrane) Compact Linear Collider, a proposed particle accelerator at CERN
Airlines Clic Air, formerly branded EasyFly, is a Colombian regional airline Clickair, former airline of Spain, merged with Vueling
Music Clic (album) a 1974 album by Italian experimental musician Franco Battiatio
Other S4C Clic, a video on demand service from Welsh broadcaster S4C CLIC Sargent (now Young Lives vs Cancer), a cancer charity in the United Kingdom Cluster LInux pour le Calcul, is a special version of Mandrakelinux for computer clusters CLiC (Colectivo de Livecoders), a livecoding collective from Argentina Community Leadership Independence Coalition, a party formed by Peter Lewis in the 2002 South Australian legislative election Company Level Intelligence Cell, a group of infantry Marines who form a small intelligence unit Cooperating Libraries in Consortium, a non-profit consortium of the libraries of eight private colleges and universities in Minneapolis–Saint Paul Programs organized by the Cumbria County Council: Cumbria Learning and Improvement Collaborative, an information resource for health and social workers Cumbria Libraries Interactive Catalogue, a county-wide public library catalogue system