H10 or H-10 may refer to:
Transportation Atlas H-10, a 1948 four-seat cabin monoplane aircraft HMS Encounter (H10), a 1934 British Royal Navy E class destroyer HMS H10, a 1915 British Royal Navy H class submarine PRR H10, a 1916 American 2-8-0 steam locomotives model H10 Bletcham Way, UK Road London Buses route H10 Lioré et Olivier LeO H-10, a French seaplane
Other Haplogroup H10 (mtDNA), a subclade of human mtDNA Haplogroup H (mtDNA) Hilbert's tenth problem in mathematics H10 Hotels, a Spanish hotel chain iriver H10 series, a series of portable digital audio players DSC-H10, a 2008 Sony Cyber-shot H series camera H-10, refrigerant leak detector from Bacharach