Giguère or Giguere is a surname. Notable people with the surname include:
Daniel Giguère (born 1957), Canadian politician Élizabeth Giguère (born 1997), Canadian ice hockey player François Giguère (born 1963), Canadian former general manager of the Colorado Avalanche Jean-Sébastien Giguère (born 1977), Canadian hockey goaltender Louis Giguère (1911–2002), Canadian senator Nathalie Giguère (born 1973), Canadian swimmer Paul-Antoine Giguère (1910–1987), Canadian academic and chemist Réal Giguère (born 1933), Canadian talk and game show host Robert Giguère (1616–1709) early pioneer in New France Samuel Giguère (born 1985), Canadian football player