River Tame is a Celtic river name, used in England to refer to:

River Tame, Greater Manchester, a river that meets the Goyt to form the Mersey River Tame, West Midlands, the largest tributary of the Trent River Tame, North Yorkshire, a tributary of the Leven and then the Tees

See also River Tamar, a river that forms part of the border between Devon and Cornwall River Thame, a river that flows through Buckinghamshire and Oxfordshire, a tributary of the Thames River Thames, a river that flows through Oxford, Reading, and London