PKS may refer to: Pammal K. Sambandam, a 2002 Tamil language comedy film Przedsiębiorstwo Komunikacji Samochodowej, Polish transport organization Parkstone railway station, station code Phi Kappa Sigma, an international fraternity Parkes Catalogue of Radio Sources, an astronomical catalogue Polyketide synthases, a family of enzymes Prosperous Justice Party (Partai Keadilan Sejahtera), Indonesia Serbian Chamber of Commerce Pallister–Killian syndrome, a rare genetic disorder