Zhangsun was a Chinese compound surname often of Xianbei origin. People with this surname included:

Zhangsun Sheng (552–609), diplomat and general of Sui dynasty Zhangsun Shunde (565–631), general of the Tang dynasty Empress Zhangsun (601–636), first empress consort of the Tang dynasty Zhangsun Wuji (died 659), prime minister of the Tang dynasty and Empress Zhangsun's brother