Esquirol means scab (strikebreaker) in Spanish, and squirrel in Catalan and Occitan. It is also a surname and may refer to:
Jean-Étienne Dominique Esquirol (1772–1840), French psychiatrist John H. Esquirol (1900–1970), American Episcopal bishop Joseph A. Esquirol (1898–1981), New York politician
See also Charenton (asylum), commonly referred to as the "Esquirol Hospital" L'Esquirol, a municipality in Catalonia