Dedekind is a German surname. Notable people with the surname include:

Brendon Dedekind (born 1976), South African swimmer Constantin Christian Dedekind (1628–1715), German poet, dramatist and composer Friedrich Dedekind (1524–1598), German humanist, theologian, and bookseller Henning Dedekind (1562–1626), German composer, grandfather of Constantin Christian Dedekind Katja Dedekind (born 2001), Australian Paralympic swimmer and goalball player Richard Dedekind (1831–1916), German mathematician 19293 Dedekind, asteroid named after Richard Dedekind