Similkameen may refer to:
Similkameen, a former community in British Columbia, Canada Similkameen City, British Columbia, a former community in British Columbia, Canada Similkameen Country or Similkameen District, or "the Similkameen", a historical georegion in British Columbia, Canada Similkameen River, a river that runs through southern British Columbia, discharging into the Okanogan River near Oroville, Washington, United States Similkameen people, or Similkameens, a branch of the Salishan-speaking Okanagan people Lower Similkameen Indian Band, a First Nations government Upper Similkameen Indian Band Similkameen (electoral district), a defunct provincial electoral district in British Columbia, Canada Boundary-Similkameen, a defunct provincial electoral district in British Columbia Regional District of Okanagan-Similkameen, a regional district in British Columbia Okanagan—Similkameen, a defunct federal electoral district in British Columbia Okanagan—Similkameen—Merritt, a defunct Canadian federal electoral district in British Columbia