John or Johnny Byrne may refer to:

Arts and entertainment John Byrne (English artist) (1786–1847), English painter and printmaker Johnny Byrne (writer) (1935–2008), former BBC editor and script writer John Byrne (playwright) (1940–2023), Scottish playwright and artist John Byrne (musician) (1946–2008), Irish-born American musician John Byrne (illustrator) (born 1950), English-born American comic book artist and writer John Byrne (Irish artist) (born 1959), Irish performance and multimedia artist John Byrne (columnist), British writer and broadcaster

Politics John Byrne (Irish politician) (1878–1942), Irish Cumann na nGaedhael politician John F. Byrne Sr. (1911–1965), American politician, member of Philadelphia City Council John F. Byrne Jr. (born 1935), American politician, member of the Pennsylvania State Senate, son of the above

Sports Association football John Byrne (Scottish footballer) (born 1939), Scottish footballer Johnny Byrne (footballer) (1939–1999), England international footballer, soccer coach in South Africa John Byrne (footballer, born 1949), English footballer for Tranmere Rovers John Byrne (footballer, born 1961), English-born footballer for QPR, Sunderland and the Republic of Ireland John Byrne (footballer, born 1962), Irish footballer

Other sports John Byrne (Australian footballer) (born 1956), Australian rules footballer for North Melbourne John Byrne (cricketer) (born 1972), Irish cricketer Jon Byrne (born 1983), Australian-born baseball umpire

Others John Byrne (VC) (1832–1879), Irish recipient of the Victoria Cross John Edgar Byrne (1842–1906), Australian journalist and newspaper proprietor John Francis Byrne, creator of the Chaocipher Jock Byrne (John Thomas Byrne, 1903–1969), Scottish trade unionist and anti-communist John Byrne (businessman) (1919–2013), Irish property developer John V. Byrne (1928–2024), American marine geologist and academic John J. Byrne (1931–2013), American insurance industry executive John Byrne (computer scientist) (1933–2016), Irish computer scientist John H. Byrne (born 1946), American neuroscientist John Byrne (judge) (born 1948), Senior Judge Administrator of the Supreme Court of Queensland John K. Byrne (born 1981), founder of the Raw Story news website

See also Jack Byrne (disambiguation) John Burn (disambiguation) John Byrnes (disambiguation) Byrne, surname