Prescott House may refer to:
Benjamin Franklin Prescott House, Epping, New Hampshire, on the National Register of Historic Places (NRHP) C. J. Prescott House, Virginia City, Nevada, on the NRHP Gustavus G. Prescott House, Somerville, Massachusetts, on the NRHP J.L. Prescott House, North Berwick, Maine, on the NRHP William H. Prescott House, Boston, Massachusetts, on the NRHP
See also Prescott Town House, Petersham, Massachusetts, on the NRHP Eaton–Prescott House, Reading, Massachusetts, on the NRHP Prescott House Museum, Starr's Point, Nova Scotia, Canada, a historic house and gardens