Elections to the South Dakota Senate were held on November 2, 1920, to elect 45 candidates to the Senate to serve a two-year term in the 17th South Dakota Legislature. Republicans retained their supermajority status in the chamber, holding 42 of the 45 Senate seats in the 17th Legislature. C. S. Amsden of Grant County was re-elected President pro tempore of the Senate.

This election took place alongside races for U.S. President, U.S. Senate, U.S. House, governor, state house, and numerous other state and local elections.

See also List of South Dakota state legislatures

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