Aminomethylsulfonic acid (also called aminomethylenesulfonic acid and aminomethanesulfonic acid) is an organic chemical compound, with amino () and sulfonic acid () groups on the carbon atom. Its chemical formula is , and it has a molar mass of 111.12 g/mol.
Synthesis Aminomethane sulfonic acid can be made by the reaction between hexamethylenetetramine (hexamine) with sulfur dioxide (SO2) in an aqueous environment.
Properties Aminomethanesulfonic acid is a corrosive solid. It could be thought of as the sulfonic acid analogue of glycine, just like aminomethylphosphonic acid is the phosphonic analogue of glycine. Its density is ~1.7 g/cm3.CSID:75612, https://www.chemspider.com/Chemical-Structure.75612.html, (accessed 16:39, Jan 15, 2026)
Aminomethanesulfonic acid appears as a white crystalline solid that dissolves readily in water. It exhibits amphoteric behavior, meaning it can act as either an acid or a base depending on the conditions. Heating the compound above 280 °C leads to decomposition, releasing sulfur dioxide and other gaseous products.
Uses Although aminomethanesulfonic acid has limited commercial use, it has been employed in research as a reagent and as a buffering agent. It has also been studied as a structural analog of taurine in biochemical research, helping to investigate metabolic pathways and sulfonic acid derivatives.
Dangers Aminomethanesulfonic acid can cause skin and eye burns; it is a dermatotoxin.
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