Manuel Molina may refer to:
Manuel Molina Zamudio (1788–1868), Bolivian revolutionary and politician (1891–1926), Mexican lawyer and politician, brother of Olegario Molina Manuel Molina Jiménez (1948–2015), Spanish flamenco guitarist, member of the duo Lole y Manuel
See also (c.1620–1660), Spanish baroque painter, listed in An account of the lives and works of the most eminent Spanish painters, sculptors and architects