San Lucas (the Spanish-language name of St. Luke) is sometimes used as a toponym:
Belize San Lucas, Belize, a village in Toledo District, Belize
Colombia Serrania of San Lucas (mountains)
Costa Rica San Lucas Island
Guatemala San Lucas Sacatepéquez (Sacatepéquez department) San Lucas Tolimán (Sololá department)
Honduras San Lucas, El Paraíso
Mexico San Lucas, Chiapas San Lucas, Michoacán San Lucas Tecopilco, Tlaxcala San Lucas Quiavini, Oaxaca San Lucas Zoquiapam, Oaxaca Cabo San Lucas, Baja California Sur
Nicaragua San Lucas, Madriz
United States San Lucas, California San Lucas AVA, California wine region in Monterey County