Clisby is a surname. Notable people with the surname include:
Harriet Clisby (1830–1931), English physician and activist Jack Clisby (born 1992), Australian soccer player Les Clisby (1914–1940), Australian fighter ace of World War II Mark Clisby, Australian lawyer, author, journalist and military historian Mitch Clisby (born 1990), Australian rules footballer
See also Clasby, surname Cleasby, village in North Yorkshire