The Ministry of Deregulation and State Transformation () of Argentina is a ministry of the national executive power. Its purpose is to help the president and chief of the Cabinet of Ministers in matters related to deregulation, reform, and modernization efforts.

The inaugural and current head of the Ministry is Federico Sturzenegger, who was appointed on 5 July 2024. The Ministry was created after the passing of the law of Bases and Starting Points for the Freedom of Argentines, which enjoys powers delegated by the government, necessary requirements to allow the Ministry to function in eliminating, modifying, or implementing decrees.

Javier Milei, the current president of Argentina, has stated that Elon Musk called Sturzenegger to discuss the United States imitating the model of the Ministry of Deregulation and State Transformation with the Department of Government Efficiency.

Jurisdiction Order 585/2024, modifies the 22 520 law, stating that the jurisdiction of the Ministry of Deregulation and State Transformation is designed:

Organization Centralized departments of the Ministry of Deregulation and State TransformationMinistrySecretaryTitleAssumed officePartyMinistry of Deregulation and State TransformationSecretary for the Simplification of the StateMartín Antonio Rossi1 August 2024IndependentSecretary for the Transformation of the State and Public FunctionsMaximiliano Fariña19 July 2024IndependentSecretary for Legal and Administrative CoordinationMarcelo Julián Hernández 1 August 2024Independent #NamePartyPeriodPresidentStartEnd1Federico SturzeneggerRepublican Proposal5 July 2024IncumbentJavier Milei

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