Manandhar is a surname. Notable people with the surname include:
Asta Narayan Manandhar (1900–1960), Nepalese entrepreneur Baikuntha Manandhar (born 1951), Nepali marathon runner Basanta Prasad Manandhar, Nepalese politician Evana Manandhar, Nepalese businesswoman Karishma Manandhar, Nepalese actress Kiran Manandhar (born 1957), Nepalese painter Melina Manandhar (born 1975), Nepalese actress Narayan Manandhar (born 1981), Nepalese footballer Ram Bir Manandhar, Nepalese politician Shanta Das Manandhar (1934–2023), Nepalese writer Shashikala Manandhar (born 1960), Nepalese novelist Sonika Manandhar (born 1990), Nepali computer engineer Sulochana Manandhar (born 1955), Nepali poet