Gugulethu is a feminine given name derived, from the Nguni word igugu lethu, meaning "our treasure/pride". Notable people with the name include:
Gugulethu Mayisela (born 2004), South African model Gugulethu Sophia Mbatha (born 1983), English actress Gugulethu Mchunu, South African politician Gugulethu Mfuphi, South African broadcast journalist Gugulethu Zuma-Ncube (born 1985), South African producer and actress
See also Gugulethu, a township in Western Cape, South Africa Gugulethu Seven, a group of South African anti-apartheid men shot by South African Police on 3 March 1986