The 1911 Washington University Pikers football team represented Washington University in St. Louis as a member of the Missouri Valley Conference (MVC) during the 1911 college football season. Led by fourth-year head coach Frank Cayou, the Pikers compiled an overall record of 4–2–2 with a mark of 0–0–2 in conference play, tying for third place in the MVC. Washington University played home games at Francis Field in St. Louis.

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