George Pyke may refer to:
George Pyke (politician) (1775–1851), lawyer, judge and political figure in Lower Canada George Pyke (footballer) (1887–1960), Australian rules footballer for Fitzroy George Woolston Pyke (1893–1977), English footballer George Alexander Pyke, Lord Tilbury, a fictional character in the stories of British author P. G. Wodehouse See also George Pike (1923–2007), Australian rules footballer for Geelong