50 series may refer to:

Electronics

HP 49/50 series, a type of graphing calculator made by Hewlett-Packard Nvidia GeForce RTX 50 series, a series of graphic cards

Trains

1–50 series (CTA), a retired subway car type for the Chicago Transit Authority EMD SD50, also known as "50 series", a North American diesel locomotive type made by Electro-Motive Diesel Kyoto Municipal Subway 50 series operating for the Kyoto Municipal Subway

Trucks

Dodge 50 Series, a box truck model operating in Europe

See also

Detroit Diesel Series 50, a diesel engine for heavy-duty vehicles