The South African Federation of Trade Unions (SAFTU) was a national trade union federation of workers representing workers in South Africa.

The federation was founded in 1951, as a split from the South African Trades and Labour Council by right-wing unions which accepted apartheid and did not approve of black workers being given a role in governing trade unions. Some of the unions which split away were restricted to white workers, while others accepted "coloured" or Asian members, but none admitted black workers.

The unions with a mixed membership, such as the South African Typographical Union, soon left to join the new Trade Union Council of South Africa, which similarly did not admit black workers. In 1957, the federation affiliated to the South African Confederation of Labour (SACOL). By 1962, it had 11 affiliates, with a total of 66,263 members. As SACOL became more centralised, SAFTU declined in importance, and it appears to have dissolved around 1980.

Union Membership (1962) Artisan Staff Association 16,611 Cape Explosives Industrial Workers' Union 486 Mine Workers' Union 17,500 Natal Aluminium Workers' Union National Association of Furniture and Allied Industries 1,516 National Baking Industrial Union Netherlands Bank of South Africa Staff Society South African Actors' Equity Association South African Airways Engineering Association 740 South African Association of Municipal Employees 18,070 South African Engine Drivers' and Firemen's Association 4,538 South African Jockeys' Association 60 South African Reduction Workers' Association 3,300 South African Teleprinter Operators' Society 270 Transvaal Explosives and Chemical Workers' Union 600 Transvaal Retail Meat Trade Employees' Union 980

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