Man-Machine or Man and Machine may refer to:
Technology
Human–computer interaction, man-machine interaction (MMI) MML (programming language), a man-machine language Cyborg, a cybernetic organism which enhances its abilities by using technology Transhumanism, the idea of human enhancement via technology
Music
The Man-Machine, a 1978 album by Kraftwerk Man vs. Machine, a 2002 album by rapper Xzibit Man and Machine (album), a 2002 album by U.D.O. Man Machine, an early '90s techno/electro project, signed to Rhythm King
Other
Machine Man, a 1977 character created by Jack Kirby for Marvel Comics Mann & Machine, a 1992 American science fiction police drama television series Ghost in the Shell 2: Man-Machine Interface, a 1997 manga by Masamune Shirow Man a Machine, a 1748 work of materialist philosophy by French physician and philosopher Julien Offray de La Mettrie Maschinenmensch ("machine-human"), a robot featured in the film Metropolis
See also Man engine, a ladder-like mechanism installed in mines