The men's 4 × 100 metres relay event at the 1963 Pan American Games was held at the Pacaembu Stadium in São Paulo on 4 May 1963.Full results

Results Rank Nation Athletes Time Notes Earl Young, Ollan Cassell, Brooks Johnson, Ira Murchison 40.40 Héctor Thomas, Horacio Esteves, Arquímides Herrera, Rafael Romero 40.71 Clifton Bertrand, Anthony Jones, Irving Joseph, Cipriani Phillip 40.87 4 Antonio Alves, Joel da Costa, Affonso da Silva, Joe Satow 41.23 5 Heriberto Cruz, Jorge Derieux, Juan Montes, Manuel Rivera 42.02 6 Victor Hernández, Lázaro Betancourt, Jorge Cumberbach, Enrique Figuerola 42.60

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