Niehoff is a surname. Notable people with this surname include:
Bert Niehoff (1884–1974), Americal baseball player Domenica Niehoff (1945–2009), German prostitute and activist Hendrik Niehoff (1495–1561), Dutch pipe organ builder Hermann Niehoff (1897–1980), German general Niklas Niehoff (born 2004), German footballer Robert L. Niehoff (born 1953), American academic administrator Robert Niehoff (born 1964), American football player
See also Doninger v. Niehoff, a 2008 United States Court of Appeals case