Rein is a surname. Notable people with the surname include:
Andrew Rein (born 1958), American wrestler Bo Rein (1945–1980), American baseball and football player David Rein (1914–1979), American attorney Hans Rein, German sprint canoeist Irving J. Rein, American communication scientist Ivan Rein (1905–1943), Croatian painter Johannes Justus Rein (1835–1918), German writer and traveler in East Asia Jeff Rein (born 1953), American businessman Jonas Rein (1760–1821), Norwegian priest, poet and politician Kristoffer Rein (1912–1993), Norwegian politician Manfred Rein (1948–2016), Austrian politician Mark Rein (journalist) (1909–1937?), Menshevik journalist Mark Rein (executive), vice president of Epic Games Mercedes Rein (1930–2006), Uruguayan writer and dramatist Ohad Rein (born 1979), Australian singer/songwriter, stage name Old Man River Paul Rein (born 1965), Swedish singer and songwriter Rosa Rein (1897–2010), German-Swiss supercentenarian Thérèse Rein (born 1958), Australian businesswoman Toomas Rein (born 1940), Estonian architect Torald Rein (born 1968), German cross country skier Torolf Rein (born 1934), Norwegian military officer Trine Rein (born 1970), Norwegian singer Wilhelm Rein (1847–1929), German educational theorist Yevgeny Rein (born 1935), Russian poet and writer
See also Rein (given name)