Maderna is a surname. Notable people with the surname include:
Bruno Maderna (1920–1973), Italian conductor and composer Carlos Maderna (1910–1976), Argentine chess master Divya Maderna (born 1984), Indian politician Ezequiel Maderna (born 1986), Argentine boxer Giovanni Maderna (born 1973), Italian film director Mahipal Maderna (born 1952), Indian politician Marianne Maderna (born 1944), Austrian installation artist Parasram Maderna (1926–2014), Indian politician