Sciacca is a surname. Notable people with the surname include:
Con Sciacca (1947–2017), Australian politician Fabio Sciacca (born 1989), Italian footballer Gary Sciacca (born 1960), American horse trainer Giacomo Sciacca (born 1996), Italian footballer Giuseppe Sciacca (born 1955), Italian Roman Catholic official Paul Sciacca (1909–1986), American mobster