The freshwater-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics. Freshwater-1 motifs are found in metagenomic sequences isolated from bacteria in Freshwater and estuary environments. Freshwater-1 RNAs likely function in trans as small RNAs. Most freshwater-1 RNAs are located between tRNA genes, although no similarity between freshwater-1 RNAs and tRNAs has been observed, as of 2018.
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