Gholson is a surname. Notable people with the surname include:
Christien Gholson, American-born writer Christopher James Gholson (born 1983), American producer and rapper Ellen Anderson Gholson Glasgow (1873–1945), American novelist James Gholson (1798–1848), American politician Richard D. Gholson (1804–1862), American lawyer and politician Samuel J. Gholson (1808–1883), American judge Thomas Gholson, multiple people William Y. Gholson (1807–1870), American judge
See also
Gholson, Mississippi Gholson, Texas