Drunella grandis is a species of spiny crawler mayfly in the family Ephemerellidae. It is found in North America.
Subspecies These three subspecies belong to the species Drunella grandis: Drunella grandis flavitincta (McDunnough, 1934) Drunella grandis grandis (Eaton, 1884) Drunella grandis ingens (McDunnough, 1934)
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