Owensboro is a city in the U.S. state of Kentucky. "Owensboro" may also refer to:
Owensboro Bridge Owensboro Catholic High School Owensboro Community and Technical College Owensboro–Daviess County Regional Airport Owensboro High School Owensboro Medical Health System Hospital Owensboro metropolitan area Owensboro and Nashville Railroad Owensboro and Nashville Railway Owensboro Oilers Owensboro Public Schools Owensboro Rage Owensboro and Russellville Railroad Owensboro Sportscenter Central City, Kentucky, formerly "Owensboro Junction." Evansville IceMen, once "Owensboro IceMen." Evansville, Owensboro and Nashville Railroad