RDR may refer to:

Entertainment Red Dead, a series of western-themed video game published by Rockstar Games, has included several games with the initials "RDR" including Red Dead Revolver, Red Dead Redemption, and Red Dead Redemption 2.

Military Grand Forks Air Force Base (IATA airport code) Rhodesian Defence Regiment, Rhodesian Security Forces unit Royal Durban Rifles, now the Durban Light Infantry

Organizations Rassemblement Démocratique pour la République, a political party in the Democratic Republic of the Congo Rassemblement Démocratique pour le Rwanda, also known as "Rassemblement Démocratique pour la Retour", an insurgent group in Rwanda Rassemblement des Républicains, a political party in Côte d'Ivoire Rat für deutsche Rechtschreibung (RdR), German-language regulator Retail Distribution Review, a review carried out by the UK Financial Services Authority into the advising of retail investment products

Science and technology Restrictive design rules, a way for a semiconductor fabrication to ensure acceptable yield on its most advanced integrated circuits Ripple down rules, a knowledge acquisition methodology RNA-dependent RNA polymerase, an enzyme for RNA production

Transportation Radyr railway station (National Rail station code) Royal Deeside Railway, a heritage railway in Scotland

Other Rangitata Diversion Race, South Island, New Zealand Registered Diplomate Reporter, a certification offered by the National Court Reporters Association Reinier de Ridder, a Dutch mixed martial artist