Brefeldia is a genus of slime molds in the family Amaurochaetaceae.

The genus name of Brefeldia is in honour of Julius Oscar Brefeld (1839 – 1925), a German botanist and mycologist.

The genus was circumscribed by Józef Tomasz Rostafínsky in 1873 and appears to be monotypic, containing the species Brefeldia maxima.Rostafínsky JT (1873) Versuch Syst. Mycetozoen (Strassburg): 8, p. 20.

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