Tsk or TSK may refer to:
Language "tsk!", a dental click Tseku language (ISO 639:tsk), a language of Tibet
Arts and media Tsk Tsk Tsk, an Australian music, art and performance group Thaanaa Serndha Koottam, a 2018 Indian Tamil-language crime comedy film by Vignesh Shivan "TSK", a song by Nas from Magic 3, 2023 San-in Chūō Television Broadcasting, a Japanese TV station
Science and technology Galoter process, shale oil extraction technology Takagi-Sugeno-Kang, a system of Fuzzy logic Terrace step kink, a model to describe the thermodynamics of crystal surface formation The Sleuth Kit, computer forensics tools Transmission security keys
Other uses Tiger Schulmann's Karate Tomsk Avia (ICAO: TSK), a Russian airline Turkish Armed Forces (Turkish: Türk Silahlı Kuvvetleri)