The Philadelphia 76ers, commonly called the "Sixers" for short, are an American professional basketball team playing in the National Basketball Association.

Sixer or Sixers may also refer to:

Sixer (2007 film), an Indian Kannada-language film Sixer (2019 film), an Indian Tamil-language film Fort Worth Sixers, a National Indoor Football League franchise in the United States Cricket: Sydney Sixers, an Australian cricket franchise Sixer (cricket), an act of scoring six runs Southern Sixers, mountains in the southern United States which are at least six thousand feet tall Stephen Kellogg and the Sixers, an American rock band Sixers, characters in the American TV series Terra Nova Sixer, a member of a Cub Pack who leads a team called a "Six" Sixers, the slang term for members of the IOI in Ready Player One