Mattiana was a Roman-Berber civitas in the province of Africa Proconsularis. The locale existed during late antiquity, and was situated in northern Tunisia.Titular Episcopal See of Mattiana, at GCatholic.org.

In antiquity, the town was also the seat of a Catholic bishopric,Pius Bonifacius Gams, Series episcoporum Ecclesiae Catholicae, (Leipzig, 1931), p. 467. Stefano Antonio Morcelli, Africa christiana, Volume I, (Brescia, 1816), p. 217. suffragan of the Archdiocese of Carthage. The historical sources mention only one known bishop, Marcellus, who took part in the Council of Carthage of 646. Today Mattiana survives as a titular bishopric Mattiana at catholic-hierarchy.org. of the Roman Catholic Church and the current bishop is José Eugenio Ramos Delgado, of Monterrey, who succeeds Carlos Alberto Salcedo Ojeda of Huancayo, Titular Episcopal See of Mattiana, at GCatholic.org. in 2026.Titular Episcopal See of Mattiana, at GCatholic.org.

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