Donatus Ó Muireadhaigh, O.S.A. (Anglicised: Donatus O'Murray; died 1485) was a fifteenth-century Archbishop of Tuam.
An Augustinian Canon, he was the Dean of Tuam before appointed Archbishop of Tuam by Pope Nicholas V on 2 December 1450., The Province of Connaught, p. 10., Handbook of British Chronology, p. 375., A New History of Ireland, volume IX, p. 320. He granted the status of collegiate church to the St. Nicholas' Collegiate Church in Galway in 1484., The Province of Connaught, pp. 10–11.
Archbishop Ó Muireadhaigh died in office on 17 January 1485., The Province of Connaught, p. 11.
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