Griffin Hollow is a valley in Ralls County in the U.S. state of Missouri. The valley stream is a tributary to the Salt River.
The stream headwaters are just northwest of Center at at an elevation of about 710 feet and the confluence with the Salt River is at with an elevation of 525 feet.Center, Missouri, 7.5 Minute Topographic Quadrangle, U.S. Geological Survey, 1991
Griffin Hollow has the name of David Griffin, the original owner of the site.
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