The Men's 50 metre freestyle S10 event at the 2016 Paralympic Games took place on 9 September 2016, at the Olympic Aquatics Stadium. No heats were held. The swimmers with the eight fastest times advanced to the final.

Heats Heat 1 10:06 9 September 2016:

Rank Lane Name Nationality Time Notes 1 5 24.01 2 4 24.34 3 6 25.04 4 3 25.08 5 2 26.59

Heat 2 10:09 9 September 2016: Rank Lane Name Nationality Time Notes 1 4 24.07 2 5 24.49 3 3 25.36 4 6 25.80 5 7 26.08 6 2 26.51

Heat 3 10:12 9 September 2016: Rank Lane Name Nationality Time Notes 1 5 23.45 2 4 24.36 3 3 25.08 4 6 25.32 5 7 25.77 6 2 26.31

Swim-off 11:39 9 September 2016: Rank Lane Name Nationality Time Notes 1 4 24.62 2 5 24.74

Final 18:45 9 September 2016:

Rank Lane Name Nationality Time Notes 4 23.33 3 23.56 5 23.75 4 2 23.78 5 6 24.00 6 7 24.09 7 8 24.47 8 1 24.84

Notes