Winchester is an unincorporated community in eastern Clark County, in the U.S. state of Missouri.

The community is located on Missouri Route H 1.5 miles west of US Route 61. Wayland is approximately five miles to the north and the community of Antioch is four miles to the west.Missouri Atlas & Gazetteer, DeLorme, First edition, 1998, p. 17

History Winchester was platted in 1837, and most likely was named after Winchester, Virginia. A post office called Winchester was established in 1840, and remained in operation until 1905.

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