Novation is a legal term in contract and business law.
Novation may also refer to:
Novation (Fringe), an episode of the Fringe television series Novation CAT, a defunct early modem manufacturer Novation Digital Music Systems, manufacturer of electronic musical equipment Novation Supernova synthesizer One of the predecessor companies of Vizient, Inc.
See also Novatian, the third century Roman bishop and theologian