Tarocin A and tarocin B are two structurally unrelated compounds that inhibit the TarO enzyme involved in teichoic acid biosynthesis in bacteria.Antibiotic Assistants; Scientists discover compounds that restore antibiotic efficacy against drug-resistant superbugs. March 2016
Using either of them with β-lactam antibiotics seems to be effective in mice against some β-lactam-resistant bacteria.
Because the tarocins lack activity when used alone it may simplify the clinical trials for approval for medical use.
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